|
N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride |
|
Escherichia |
Biofilm |
Preclinical (in vitro) |
Bunders CA, et al. 2010. Bioorg Med Chem Lett |
|
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-difluorobenzamide;hydrochloride |
Depiction based on curated SMILES
N
H
ClH
F
F
O
H
2
N
N
H
N
|
Escherichia Pseudomonas |
Biofilm Biofilm |
Preclinical (in vitro) Preclinical (in vitro) |
Bunders CA, et al. 2010. Bioorg Med Chem Lett
|
|
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride |
Depiction based on curated SMILES
N
H
ClH
H
2
N
N
H
N
CH
3
O
|
Escherichia |
Biofilm |
Preclinical (in vitro) |
Bunders CA, et al. 2010. Bioorg Med Chem Lett |
|
N-[[(E)-(3,5-dichloro-2-hydroxyphenyl)methylideneamino]carbamothioyl]-2,2-dimethylpropanamide |
Depiction based on curated SMILES
N
OH
Cl
Cl
CH
3
NH
S
N
H
O
H
3
C
H
3
C
|
Escherichia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Gauthier A, et al. 2005. Antimicrob Agents Chemother |
|
Tyrphostin 51 |
Depiction based on curated SMILES
NH
2
N
N
N
OH
OH
OH
|
Francisella Mycobacterium |
Acid phosphatase Exoenzyme |
Preclinical (in vitro) Preclinical (in vitro) |
Fernández-Soto P, et al. 2021. Sci Rep
|
|
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-dichlorobenzamide |
Depiction based on curated SMILES
NH
2
Cl
Cl
O
N
H
N
H
N
|
Francisella |
Regulation |
Preclinical (in vitro) |
Milton ME, et al. 2017. Mol Microbiol |
|
(4Z)-2-benzyl-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-(trifluoromethyl)pyrazol-3-one |
Depiction based on curated SMILES
Br
F
F
F
O
H
3
C
N
N
O
|
Haemophilus |
LOS |
Preclinical (in vitro) |
Xu Y, et al. 2018. Bioorg Med Chem |
|
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-(benzyloxy)benzylidene]-2-pyrazoline-5-one |
Depiction based on curated SMILES
F
F
F
O
N
N
O
|
Haemophilus |
LOS |
Preclinical (in vitro) |
Xu Y, et al. 2018. Bioorg Med Chem |
|
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-bromo-4-methoxybenzylidene]-2-pyrazoline-5-one |
Depiction based on curated SMILES
Br
F
F
F
O
H
3
C
N
N
O
|
Haemophilus |
LOS |
Preclinical (in vitro) |
Xu Y, et al. 2018. Bioorg Med Chem |
|
(4Z)-4-[(4-chlorophenyl)methylidene]-2-phenyl-5-(trifluoromethyl)pyrazol-3-one |
Depiction based on curated SMILES
F
F
F
N
Cl
O
N
|
Haemophilus |
LOS |
Preclinical (in vitro) |
Xu Y, et al. 2018. Bioorg Med Chem |
|
| | |