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Compound category: Benzenoids
(total 233 related compounds in database, current show from 111 to 120)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride Depiction based on curated SMILES HN ClH H 2 N N H N H 3 C O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-difluorobenzamide;hydrochloride Depiction based on curated SMILES N H ClH F F O H 2 N N H N Escherichia
Pseudomonas
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-4-pentylbenzamide;hydrochloride Depiction based on curated SMILES N H ClH H 2 N N H N CH 3 O Escherichia Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
N-[[(E)-(3,5-dichloro-2-hydroxyphenyl)methylideneamino]carbamothioyl]-2,2-dimethylpropanamide Depiction based on curated SMILES N OH Cl Cl CH 3 NH S N H O H 3 C H 3 C Escherichia TTSS (Type III secretion system) Preclinical (in vitro) Gauthier A, et al. 2005. Antimicrob Agents Chemother
Tyrphostin 51 Depiction based on curated SMILES NH 2 N N N OH OH OH Francisella
Mycobacterium
Acid phosphatase
Exoenzyme
Preclinical (in vitro)
Preclinical (in vitro)
Fernández-Soto P, et al. 2021. Sci Rep
N-[4-(2-amino-1H-imidazol-5-yl)phenyl]-3,5-dichlorobenzamide Depiction based on curated SMILES NH 2 Cl Cl O N H N H N Francisella Regulation Preclinical (in vitro) Milton ME, et al. 2017. Mol Microbiol
(4Z)-2-benzyl-4-[(3-bromo-4-methoxyphenyl)methylidene]-5-(trifluoromethyl)pyrazol-3-one Depiction based on curated SMILES Br F F F O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-(benzyloxy)benzylidene]-2-pyrazoline-5-one Depiction based on curated SMILES F F F O N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
1-Phenyl-3-(trifluoromethyl)-4-[(Z)-3-bromo-4-methoxybenzylidene]-2-pyrazoline-5-one Depiction based on curated SMILES Br F F F O H 3 C N N O Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
(4Z)-4-[(4-chlorophenyl)methylidene]-2-phenyl-5-(trifluoromethyl)pyrazol-3-one Depiction based on curated SMILES F F F N Cl O N Haemophilus LOS Preclinical (in vitro) Xu Y, et al. 2018. Bioorg Med Chem
   


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