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Compound category: Carboxylic acids and derivatives
(total 141 related compounds in database, current show from 91 to 100)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
1-[3-(Trifluoromethyl)benzyl]-5-nitro-3'-(3,4-difluorophenyl)spiro[1H-indole-3(2H),2'-thiazolidine]-2,4'-dione 1',1'-dioxide Depiction based on curated SMILES + N O _ O F N F F S O O O N O F F Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
3'-(3-Chloro-4-fluorophenyl)-1-(3,4-difluorobenzyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide Depiction based on curated SMILES N + N O _ O Cl F N S O O O O F F Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
1-(3-Chlorobenzyl)-3'-(3-chloro-4-fluorophenyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide Depiction based on curated SMILES N + N O _ O Cl F N S O O O O Cl Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
1-(4-Chlorobenzyl)-3'-(3-chloro-4-fluorophenyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide Depiction based on curated SMILES N + N O _ O Cl F N S O O O O Cl Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
3'-(3-Chloro-4-fluorophenyl)-5-nitro-1-[3-(trifluoromethyl)benzyl]-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide Depiction based on curated SMILES + N O _ O F N Cl F S O O O N O F F Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
3-decyl-1-(furan-2-carbonyl)-2-methylindole-5-sulfonic acid Depiction based on curated SMILES CH 3 O O HO O O S CH 3 N Mycobacterium Exoenzyme Preclinical (in vitro) Nören-Müller A, et al. 2006. Proc Natl Acad Sci U S A
ZTB23(R) Depiction based on curated SMILES O S S HO O N HO O H Mycobacterium Exoenzyme Preclinical (in vitro) Mori M, et al. 2014. Bioorg Med Chem Lett
4-[[3-(3,4-difluorophenyl)-5'-nitro-1,1,2',4-tetraoxo-spiro[1,3-thiazolidine-2,3'-indoline]-1'-yl]methyl]benzonitrile Depiction based on curated SMILES N F F O S O O O N N + N O _ O Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
N-[(Z)-(2-hydroxy-3-prop-2-enylphenyl)methylideneamino]-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide Depiction based on curated SMILES N H N CH 2 O N H N HO Mycobacterium Motility Preclinical (in vitro) Ouertatani-Sakouhi H, et al. 2017. PLoS One
1-[2-[(4-fluorophenyl)methylamino]-2-oxo-ethyl]-N-[1-(4-methyl-5-vinyl-1H-imidazol-2-yl)ethyl]-6-oxo-pyridine-3-carboxamide Depiction based on curated SMILES H 2 C F NH O CH 3 O N O NH H 3 C N H N Mycobacterium Exoenzyme Preclinical (in vitro) Mori M, et al. 2014. Bioorg Med Chem Lett
   


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