|
| 3-Methylthio-1,4-diphenyl-1H-1,3,4-triazolium |
|
Escherichia |
Heat-labile toxin (LT) |
Preclinical (in vivo) |
Hovey BT, et al. 1999. J Mol Biol |
|
| (3R)-5-Oxo-6-(dimethylaminomethyl)-7-(1-naphthylmethyl)-8-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3beta-carboxylic acid lithium salt |
|
Escherichia |
Type 1 fimbriae; P fimbriae |
Preclinical (in vivo) |
Pinkner JS, et al. 2006. Proc Natl Acad Sci U S A |
|
| (2R,3S,4S,5S,6R)-2-[(R)-hydroxy-(4-isoquinolin-5-yl-2-methylphenyl)methyl]-6-(hydroxymethyl)oxane-3,4,5-triol |
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
| (2R,3S,4S,5S,6R)-2-[(R)-[4-(1-aminoisoquinolin-7-yl)-2-methylphenyl]-hydroxymethyl]-6-(hydroxymethyl)oxane-3,4,5-triol |
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
| 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-amine |
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
| 7-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-2H-isoquinolin-1-one |
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
| 7-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-3,4-dihydro-2H-isoquinolin-1-one |
|
Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
|
| Norharmane |
|
Escherichia
Pseudomonas |
Biofilm
Biofilm |
Preclinical (in vivo)
Preclinical (in vitro) |
Lee JH, et al. 2017. Phytomedicine
|
|
| 2-[4-[3-(furan-2-yl)-5-phenyl-1,2-oxazol-4-yl]phenyl]quinoline-4-carboxylic acid |
|
Escherichia
Salmonella |
TTSS (Type III secretion system)
TTSS (SPI-2 encode) |
Preclinical (in vitro)
Preclinical (in vitro) |
El Qaidi S, et al. 2018. Front Cell Infect Microbiol
|
|
| 5-cyano-6-[(4-methylphenyl)methylsulfanyl]pyridine-2-carboxylic acid |
|
Escherichia
Yersinia |
TTSS (Type III secretion system)
TTSS (Type III secretion system) |
Preclinical (in vitro)
Preclinical (in vitro) |
Pan NJ, et al. 2009. Antimicrob Agents Chemother
|
|
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