|
Compound 13
(internal name in literature) |
|
Vibrio |
TCP (Toxin-coregulated pilus) |
Preclinical (in vitro) |
Woodbrey AK, et al. 2018. Biochemistry |
|
| (4E)-2-(3,4-dichlorophenyl)-4-(3,4,5-trimethoxybenzylidene)-1,3-oxazol-5(4H)-one |
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Hu X, et al. 2013. Bioorg Med Chem Lett |
|
| (E)-3-(4-fluorophenyl)-N-[4-(1-hydroxy-5-methyl-6-nitrobenzimidazol-2-yl)phenyl]prop-2-enamide |
|
Yersinia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Kim OK, et al. 2009. J Med Chem |
|
| (E)-N-[4-(1-hydroxy-6-nitrobenzimidazol-2-yl)phenyl]-3-(4-methoxyphenyl)prop-2-enamide |
|
Yersinia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Kim OK, et al. 2009. J Med Chem |
|
| Imidocarb |
|
Escherichia
Yersinia |
TTSS (Type III secretion system)
TTSS (Type III secretion system) |
Preclinical (in vitro)
Preclinical (in vitro) |
Pan NJ, et al. 2009. Antimicrob Agents Chemother
|
|
| 1,3-dioxo-2-[4-(4-phenylquinazolin-2-yl)phenyl]-2,3-dihydro-1H-isoindole-5-carboxylic acid |
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Eriksson J, et al. 2012. Adv Exp Med Biol |
|
| 1,6-dimethyl-3-(thiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione |
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Hu X, et al. 2013. Bioorg Med Chem Lett |
|
| N-(1,3-dimethyl-2-oxo-6-pyrrolidin-1-yl-2,3-dihydro-1H-benzimidazol-5-yl)-N'-(3,4-dimethylphenyl)urea |
|
Yersinia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Harmon DE, et al. 2010. Antimicrob Agents Chemother |
|
| 1-[(5Z)-5-(1-butyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]piperidine-4-carboxamide |
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Hu X, et al. 2013. Bioorg Med Chem Lett |
|
| 1-{4-[(2-nitrophenyl)sulfonyl]piperazin-1-yl}-2-phenoxyethanone |
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Hu X, et al. 2013. Bioorg Med Chem Lett |
|
| | | |
