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Compound category: Organic compounds
(total 903 related compounds in database, current show from 881 to 890)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(3Z)-5-bromo-3-{4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}-1,3-dihydro-2H-indol-2-one Depiction based on curated SMILES S O F F F N O S Br NH Yersinia TTSS secreted effectors Preclinical (in vitro) Hu X, et al. 2013. Bioorg Med Chem Lett
5-cyano-6-[(4-methylphenyl)methylsulfanyl]pyridine-2-carboxylic acid Depiction based on curated SMILES N N HO O CH 3 S Escherichia
Yersinia
TTSS (Type III secretion system)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vitro)
Pan NJ, et al. 2009. Antimicrob Agents Chemother
5-[3'-(4-methylphenyl)-1'-phenyl-5-(2-thienyl)-3,4-dihydro-1'H,2H-3,4'-bipyrazol-2-yl]-5-oxopentanoic acid Depiction based on curated SMILES O S N N O OH N N CH 3 Yersinia TTSS (Type III secretion system) Preclinical (in vitro) Pan NJ, et al. 2009. Antimicrob Agents Chemother
5-[5-[(E)-3-[[(1S)-1-carboxy-2-(4-nitrophenyl)ethyl]amino]-3-oxoprop-1-enyl]furan-2-yl]-2-hydroxybenzoic acid Depiction based on curated SMILES + N O N H O _ O O OH O O OH OH Yersinia TTSS secreted effectors Preclinical (in vitro) Leone M, et al. 2010. Chem Biol Drug Des
5-[5-[(E)-3-[[3-[[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]amino]-3-oxopropyl]amino]-3-oxoprop-1-enyl]furan-2-yl]-2-hydroxybenzoic acid Depiction based on curated SMILES O N H N N H F F S O O OH HO O Yersinia TTSS secreted effectors Preclinical (in vitro) Leone M, et al. 2010. Chem Biol Drug Des
(Z)-5-(5-((2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-hydroxybenzoic acid Depiction based on curated SMILES S O OH HO O O O HN Yersinia TTSS secreted effectors Preclinical (in vitro) Tautz L, et al. 2005. J Biol Chem
5-[5-(2,3-Dihydro-6,7-dimethyl-3-oxothiazolo[3,2-a]benzimidazole-2-ylidenemethyl)-2-furanyl]-2-hydroxybenzoic acid Depiction based on curated SMILES N S HO O OH O CH 3 O N CH 3 Yersinia TTSS secreted effectors Preclinical (in vitro) Tautz L, et al. 2005. J Biol Chem
5-[5-[(Z)-[[6-(4-fluoroanilino)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-yl]hydrazinylidene]methyl]furan-2-yl]-2-hydroxybenzoic acid Depiction based on curated SMILES O N HO O OH F NH N N O N N NH Yersinia TTSS secreted effectors Preclinical (in vitro) Hu X, et al. 2013. Bioorg Med Chem Lett
5-({1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylene)-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione Depiction based on curated SMILES Cl O CH 3 N O S H 3 C N N O N Yersinia TTSS secreted effectors Preclinical (in vitro) Hu X, et al. 2013. Bioorg Med Chem Lett
5-({(E)-[2-(4-chlorophenyl)-5-oxo-1,3-oxazol-4(5H)-ylidene]methyl}amino)-2-hydroxybenzoic acid Depiction based on curated SMILES HO O O Cl O N N H HO Yersinia TTSS secreted effectors Preclinical (in vitro) Hu X, et al. 2013. Bioorg Med Chem Lett
   


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