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Compound category: Organoheterocyclic compounds
(total 322 related compounds in database, current show from 231 to 240)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-(4-methoxyphenyl)-2-[(6-nitro-1H-benzimidazol-2-yl)sulfanyl]acetamide Depiction based on curated SMILES N N H _ O O + N CH 3 S O N H O Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
N-(4-methylphenyl)-2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]acetamide Depiction based on curated SMILES N H _ O O + N CH 3 N S O N H Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
N-[3-(2-amino-1H-imidazol-5-yl)phenyl]heptanamide;hydrochloride Depiction based on curated SMILES ClH NH 2 N H N H 3 C HN O Pseudomonas Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
Heptanoic acid [4-(2-amino-3H-imidazol-4-yl)phenyl]amide hydrochloride Depiction based on curated SMILES ClH H 2 N N H N H 3 C N H O Pseudomonas Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
3-(furan-2-ylmethyl)-2-(((5-hydroxy-1H-pyrazol-3-yl)methyl)thio)-6,7-dihydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4(5H)-one Depiction based on curated SMILES S O N O OH NH N S N Acinetobacter
Salmonella
Biofilm
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Koopman JA, et al. 2015. Antimicrob Agents Chemother
5-Hydroxyindole Depiction based on curated SMILES OH N H Salmonella
Shigella
TTSS (SPI-1 encode)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vitro)
McShan AC, et al. 2016. ChemMedChem
Dey S, et al. 2017. ChemMedChem
Indole-3-acetic acid Depiction based on curated SMILES O OH N H Salmonella TTSS (SPI-1 encode) Preclinical (in vitro) McShan AC, et al. 2016. ChemMedChem
2-[4-[3-(furan-2-yl)-5-phenyl-1,2-oxazol-4-yl]phenyl]quinoline-4-carboxylic acid Depiction based on curated SMILES O N O N HO O Escherichia
Salmonella
TTSS (Type III secretion system)
TTSS (SPI-2 encode)
Preclinical (in vitro)
Preclinical (in vitro)
El Qaidi S, et al. 2018. Front Cell Infect Microbiol
4-Morpholinoaniline Depiction based on curated SMILES NH 2 N O Salmonella
Shigella
TTSS (SPI-1 encode)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vitro)
McShan AC, et al. 2016. ChemMedChem
Dey S, et al. 2017. ChemMedChem
4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole Depiction based on curated SMILES N HN N N N Salmonella Biofilm Preclinical (in vitro) Robijns SC, et al. 2012. FEMS Immunol Med Microbiol
   


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