|
| 4-(6-bromo-1-propylindol-3-yl)pyrimidin-2-amine |
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
| Meridianin D |
|
Mycobacterium
Staphylococcus |
Biofilm
Biofilm |
Preclinical (in vitro)
Preclinical (in vitro) |
Zeiler MJ, et al. 2020. ChemMedChem; Brackett SM, et al. 2020. RSC Med Chem
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
| 4-(6-iodo-1H-indol-3-yl)pyrimidin-2-amine |
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
| 5-(5-bromo-1H-indol-3-yl)-1H-imidazol-2-amine |
|
Staphylococcus |
Biofilm |
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
| 5-(6-bromo-1H-indol-3-yl)-1H-imidazol-2-amine |
|
Mycobacterium
Staphylococcus |
Biofilm
Biofilm |
Preclinical (in vitro)
Preclinical (in vitro) |
Brackett SM, et al. 2020. RSC Med Chem
Huggins WM, et al. 2018. ACS Med Chem Lett |
|
| 5-methyl-2-phenyl-4-[(2,4,6-tribromophenyl)iminomethyl]-1H-pyrazole-3-thione |
|
Staphylococcus |
Others |
Preclinical (in vitro) |
Suree N, et al. 2009. Bioorg Med Chem |
|
| 5-methyl-4-{[(4-nitrophenyl)amino]methylene}-2-phenyl-2,4-dihydro-3H-pyrazole-3-thione |
|
Staphylococcus |
Others |
Preclinical (in vitro) |
Suree N, et al. 2009. Bioorg Med Chem |
|
| methyl 2-morpholin-4-yl-5-[[(E)-3-thiophen-2-ylprop-2-enyl]amino]benzoate |
|
Staphylococcus |
Others |
Preclinical (in vitro) |
Chenna BC, et al. 2010. Eur J Med Chem |
|
| N-benzyl-4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine |
|
Mycobacterium
Staphylococcus |
Biofilm
Biofilm |
Preclinical (in vitro)
Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett; Zeiler MJ, et al. 2020. ChemMedChem; Brackett SM, et al. 2020. RSC Med Chem
|
|
| 5-amino-1-(5-chloro-2-methylphenyl)-4-(6-methyl-1H-benzimidazol-2-yl)-1,2-dihydro-3H-pyrrol-3-one |
|
Vibrio |
Stress survival |
Preclinical (in vitro) |
Stanbery L, et al. 2017. Drug Des Devel Ther |
|
| | | |
