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Compound category: Organoheterocyclic compounds
(total 322 related compounds in database, current show from 291 to 300)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
3-(4-fluorophenyl)-2-methyl-5-{[(4-methylphenyl)sulfanyl]methyl}pyrazolo[1,5-a]pyrimidin-7(4H)-one Depiction based on curated SMILES N F H 3 C N H N CH 3 O S Vibrio Stress survival Preclinical (in vitro) Stanbery L, et al. 2017. Drug Des Devel Ther
3-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol Depiction based on curated SMILES N H F F F OH N Vibrio Post-translational modification Preclinical (in vitro) Wang G, et al. 2022. ChemMedChem
4,4'-[(5,5-Dioxidodibenzo[b,d]thiene-2,8-diyl)bis(oxy)]diphthalonitrile Depiction based on curated SMILES N O N S O O N O N Vibrio VAS T6SS Preclinical (in vitro) Sun K, et al. 2014. Antimicrob Agents Chemother
Isonaamine A Depiction based on curated SMILES HO N H 2 N OH N Vibrio Biofilm Preclinical (in vitro) Mai T, et al. 2015. Lett Appl Microbiol
Isonaamine D Depiction based on curated SMILES N HO H 2 N N CH 3 O Vibrio Biofilm Preclinical (in vitro) Mai T, et al. 2015. Lett Appl Microbiol
5-chloro-N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothien-3-yl)-2-(ethylsulfonyl)pyrimidine-4-carboxamide Depiction based on curated SMILES Cl O O S Cl H 3 C N O N N O O S Vibrio Stress survival Preclinical (in vitro) Stanbery L, et al. 2017. Drug Des Devel Ther
Isonaamidine A Depiction based on curated SMILES OH OH H 3 C N N N H O N H O N Vibrio Biofilm Preclinical (in vitro) Mai T, et al. 2015. Lett Appl Microbiol
E676-4861 Depiction based on curated SMILES O O H 3 C CH 3 CH 3 S N N H 3 C N Vibrio Stress survival Preclinical (in vitro) Stanbery L, et al. 2017. Drug Des Devel Ther
3-(4-CHLOROPHENYL)-N-[2-(DIMETHYLAMINO)ETHYL]-5-METHYL-2-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE Depiction based on curated SMILES N Cl F F F CH 3 CH 3 CH 3 N H N N N Vibrio Stress survival Preclinical (in vitro) Stanbery L, et al. 2017. Drug Des Devel Ther
VL-AuNPs
(internal name in literature)
Depiction based on curated SMILES S NH O S O HO N O O HN Vibrio TCP (Toxin-coregulated pilus) Preclinical (in vitro) Jana SK, et al. 2021. ACS Appl Bio Mater
   


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