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Anti-virulence compounds related to VFcategory Regulation
(total 56 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-(2-{(2Z)-2-[1-(1,3-benzodioxol-5-ylmethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)pyridine-3-carboxamide Depiction based on curated SMILES O N O N H O O N N H N O Acinetobacter Regulation Preclinical (in vivo) Trebosc V, et al. 2022. Virulence
1-phenyl-3-[4-(phenylsulfamoyl)phenyl]thiourea Depiction based on curated SMILES NH S N H O HN O S Escherichia
Salmonella
Regulation
QseBC
Preclinical (in vivo)
Preclinical (in vivo)
Rasko DA, et al. 2008. Science
Dephostatin Depiction based on curated SMILES CH 3 N OH HO N O Salmonella PmrAB; SsrAB Preclinical (in vivo) Tsai CN, et al. 2020. Cell Chem Biol
5-Dodecanolide Depiction based on curated SMILES CH 3 O O Streptococcus Biofilm; Regulation Preclinical (in vivo) Valliammai A, et al. 2020. Life Sci
2',4'-Dihydroxychalcone Depiction based on curated SMILES HO OH O Vibrio HlyU Preclinical (in vivo) Imdad S, et al. 2018. Molecules
N-(4-oxo-4H-thieno[3,4-c]chromen-3-yl)-3-phenylprop-2-ynamide Depiction based on curated SMILES S O O O N H Vibrio HlyU Preclinical (in vivo) Lee ZW, et al. 2019. Sci Rep
Fursultiamin Depiction based on curated SMILES N NH 2 O S S OH CH 3 CH 3 O N N Vibrio HlyU Preclinical (in vivo) Imdad S, et al. 2018. Front Cell Infect Microbiol
Sanguinarine Depiction based on curated SMILES O O O H 3 C O + N Aeromonas Biofilm; Regulation Preclinical (in vivo) Zhang L, et al. 2022. Pathogens
Maprotiline Depiction based on curated SMILES H 3 C N H Francisella Regulation Preclinical (in vivo) Dean SN, et al. 2015. Virulence
Ethoxzolamide Depiction based on curated SMILES CH 3 O N S S O O NH 2 Mycobacterium Regulation Preclinical (in vivo) Johnson BK, et al. 2015. Antimicrob Agents Chemother
   


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