|
2-hydroxy-N-[(Z)-1-(4-phenylphenyl)ethylideneamino]benzamide |
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Paschos A, et al. 2011. Infect Immun |
|
2-hydroxy-N-[(Z)-[5-(2-nitrophenyl)furan-2-yl]methylideneamino]benzamide |
Depiction based on curated SMILES
_
O
HO
O
O
O
+
N
N
N
H
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Paschos A, et al. 2011. Infect Immun; Smith MA, et al. 2012. Chem Biol |
|
2-[3-[(5E)-5-[3-[3-(2-carboxyanilino)-3-oxopropyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoylamino]benzoic acid |
Depiction based on curated SMILES
S
S
O
N
H
N
O
HO
S
S
O
O
HO
HN
N
O
O
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Paschos A, et al. 2011. Infect Immun |
|
3-hydroxy-N-[(Z)-[5-(2-nitrophenyl)furan-2-yl]methylideneamino]benzamide |
Depiction based on curated SMILES
NH
_
O
O
+
N
OH
O
N
O
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Smith MA, et al. 2012. Chem Biol |
|
3-[(4-Methoxyanilino)carbonyl]-1,2,2-trimethylcyclopentanecarboxylic acid |
Depiction based on curated SMILES
CH
3
CH
3
HO
O
CH
3
CH
3
O
N
H
O
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Paschos A, et al. 2011. Infect Immun |
|
4-amino-N-[(Z)-[5-(3-chlorophenyl)furan-2-yl]methylideneamino]-1,2,5-oxadiazole-3-carboxamide |
Depiction based on curated SMILES
O
Cl
NH
2
N
N
H
O
N
O
N
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Paschos A, et al. 2011. Infect Immun |
|
4-hydroxy-2-oxo-N,4-diphenylbut-3-enamide |
Depiction based on curated SMILES
O
N
H
O
OH
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Paschos A, et al. 2011. Infect Immun |
|
N-[[amino(pyridin-2-yl)methylidene]amino]-5-methyl-2-nitrobenzamide |
Depiction based on curated SMILES
N
H
N
NH
N
H
CH
3
O
_
O
O
+
N
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Paschos A, et al. 2011. Infect Immun |
|
UM0125848 (internal name in literature) |
Depiction based on curated SMILES
_
O
OH
OH
O
O
O
+
N
N
N
H
|
Brucella |
VirB type IV secretion system |
Preclinical (in vivo) |
Smith MA, et al. 2012. Chem Biol |
|
(3S)-3-amino-1-[4-[2-(4-tert-butylphenyl)ethynyl]phenyl]-4-(1H-imidazol-5-yl)butan-2-one |
Depiction based on curated SMILES
H
2
N
HN
N
H
O
CH
3
CH
3
CH
3
|
Brucella |
Others |
Preclinical (in vitro) |
Abdo MR, et al. 2011. Org Biomol Chem |
|
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