|
8-hydroxy-7-(p-tolylsulfonyl)-5-(p-tolylsulfonylamino)quinoline |
|
Vibrio |
Stress survival |
Preclinical (in vitro) |
Stanbery L, et al. 2017. Drug Des Devel Ther |
|
Compound 1 (internal name in literature) |
Depiction based on curated SMILES
HO
O
CH
3
|
Vibrio |
TCP (Toxin-coregulated pilus) |
Preclinical (in vitro) |
Woodbrey AK, et al. 2018. Biochemistry |
|
Compound 2 (internal name in literature) |
Depiction based on curated SMILES
HO
O
H
3
C
|
Vibrio |
TCP (Toxin-coregulated pilus) |
Preclinical (in vitro) |
Woodbrey AK, et al. 2018. Biochemistry |
|
Compound 3 (internal name in literature) |
Depiction based on curated SMILES
OH
O
CH
3
|
Vibrio |
TCP (Toxin-coregulated pilus) |
Preclinical (in vitro) |
Woodbrey AK, et al. 2018. Biochemistry |
|
Compound 4 (internal name in literature) |
Depiction based on curated SMILES
OH
O
CH
3
|
Vibrio |
TCP (Toxin-coregulated pilus) |
Preclinical (in vitro) |
Woodbrey AK, et al. 2018. Biochemistry |
|
Imidocarb |
Depiction based on curated SMILES
O
NH
N
NH
N
H
NH
N
|
Escherichia Yersinia |
TTSS (Type III secretion system) TTSS (Type III secretion system) |
Preclinical (in vitro) Preclinical (in vitro) |
Pan NJ, et al. 2009. Antimicrob Agents Chemother
|
|
N-(1,3-dimethyl-2-oxo-6-pyrrolidin-1-yl-2,3-dihydro-1H-benzimidazol-5-yl)-N'-(3,4-dimethylphenyl)urea |
Depiction based on curated SMILES
CH
3
CH
3
N
O
H
3
C
N
N
CH
3
N
H
O
N
H
|
Yersinia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Harmon DE, et al. 2010. Antimicrob Agents Chemother |
|
1-{4-[(2-nitrophenyl)sulfonyl]piperazin-1-yl}-2-phenoxyethanone |
Depiction based on curated SMILES
S
_
O
O
+
N
O
O
O
N
N
O
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Hu X, et al. 2013. Bioorg Med Chem Lett |
|
2-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-5-chloro-N-(3,4-dichlorophenyl)benzamide |
Depiction based on curated SMILES
Cl
Cl
N
H
O
Cl
N
H
O
O
S
N
S
N
|
Yersinia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Kauppi AM, et al. 2003. Chem Biol |
|
2-chloro-4-{5-[(E)-2-(4,6-dihydroxy-5-nitropyrimidin-2-yl)ethenyl]furan-2-yl}benzoic acid |
Depiction based on curated SMILES
O
NH
O
_
O
O
+
N
HO
N
O
Cl
OH
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Eriksson J, et al. 2012. Adv Exp Med Biol |
|
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