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Compound category: Organoheterocyclic compounds
(total 34 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(S)-(-)-Indoline-2-carboxylic acid Depiction based on curated SMILES N H O OH Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
2-(3-hydroxy-2,7-diiodo-6-oxoxanthen-9-yl)benzoic acid Depiction based on curated SMILES HO O I OH I O O Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
Mordant Orange 1 Depiction based on curated SMILES _ O O + N OH O HO N N Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
2-Oxo-6-Pentyl-2H-Pyran-3-Carboxylic Acid Depiction based on curated SMILES CH 3 O O O OH Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
Gallocyanine Depiction based on curated SMILES HO O OH O HO CH 3 N CH 3 N Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
N-[2-[4-(benzimidazol-1-yl)anilino]-2-oxoethyl]-3-chloro-1-benzothiophene-2-carboxamide Depiction based on curated SMILES N H N N O S Cl O N H Salmonella
Yersinia
TTSS (SPI-1 encode)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vivo)
Boonyom R, et al. 2022. J Genet Eng Biotechnol
Swietnicki W, et al. 2011. PLoS One
N-[4-(1-hydroxy-6-nitrobenzimidazol-2-yl)phenyl]-4-(1,3-oxazol-5-yl)benzamide Depiction based on curated SMILES HO N N + N O _ O N H O O N Yersinia TTSS (Type III secretion system) Preclinical (in vivo) Garrity-Ryan LK, et al. 2010. Infect Immun
[1-(1H-indol-3-yl)-1-oxopropan-2-yl] 2-(4-acetamidophenyl)-1,3-dioxoisoindole-5-carboxylate Depiction based on curated SMILES CH 3 O N H O O N H N CH 3 O O O Burkholderia
Yersinia
Bsa T3SS
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vivo)
Swietnicki W, et al. 2011. PLoS One
(2Z)-2-(3-chloro-5-ethoxy-4-hydroxybenzylidene)-7,8-dimethyl[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one Depiction based on curated SMILES H 3 C OH Cl O N H 3 C CH 3 N S O Pseudomonas
Yersinia
TTSS (Type III secretion system)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vitro)
Harmon DE, et al. 2010. Antimicrob Agents Chemother
(E)-3-(4-fluorophenyl)-N-[4-(1-hydroxy-5-methyl-6-nitrobenzimidazol-2-yl)phenyl]prop-2-enamide Depiction based on curated SMILES O N H 3 C + N _ O N OH H F O N Yersinia TTSS (Type III secretion system) Preclinical (in vitro) Kim OK, et al. 2009. J Med Chem
   


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